Content created by Office for Human Research Protections (OHRP)
The Common Rule was revised in 2017 and is officially referred to as the 2018 Requirements.
- Visit OHRP’s Regulations page for regulatory text and associated details.
- Access information on Common Rule departments and agencies.
- Read historical details about the 2017 revision and access the Preamble to the 2018 Requirements.
OHRP Webinars on the Common Rule and Other Subparts
The U.S. Department of Health and Human Services codified its regulations for the protection of human subjects in research in the code of federal regulations at 45 C.F.R. 46, which includes five subparts. The Common Rule refers to Subpart A.
Since 2022, OHRP has created a series of webinars providing detailed explanations on the applicability of the regulations. Join our listserv to get updates on latest offerings.
You can also access short videos highlighting specific changes in the revised Common Rule. These videos were released in 2018 following the publication of the revisions. They can help viewers understand the differences between the older version (pre-2018) and the current version (2018 Requirements) of the Common Rule.
OHRP Guidance Documents on the Revised Common Rule
- Policy guidance documents
- Decision Charts for making determinations on whether projects are nonexempt human subjects research