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Medication-assisted treatment (MAT), including opioid treatment programs (OTPs), combines behavioral therapy and medications to treat substance use disorders.
Substance Use Disorder Treatment Options
There are three medications commonly used to treat opioid addiction:
- Methadone - Clinic-based opioid agonist that does not block other narcotics while preventing withdrawal while taking it; daily liquid dispensed only in specialty regulated opioid treatment clinics.
- Buprenorphine - First medication to treat Opioid Use Disorder (OUD) that can be prescribed or dispensed in physician offices, significantly increasing access to treatment.
- Naltrexone - Non-addictive opioid antagonist that blocks the effects of other narcotics; daily pill or monthly injection. Administered in a healthcare provider's office.
Check with your doctor on the right one for you.
Shared Decision-Making Tools
Learn about tools that help you and your health provider make a recovery plan.
Information about Medications for Opioid Use Disorder (MOUD)
FDA is working to facilitate treatment options and develop therapies to address OUD, promote treatment awareness, and expand treatment access.
Need help?
SAMHSA National Helpline
Get treatment referral and information about mental health and drug or alcohol use disorders, prevention, and recovery.
FindTreatment.gov
Millions of Americans have mental and substance use disorders. Find a comprehensive list of certified treatment programs across the United States.