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    • About HHS

      HHS is a U.S. executive department that touches the lives of nearly all Americans by protecting your rights, research, food safety, health care, aging, and much more.

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      HHS is advancing the Make America Healthy Again agenda by putting nutrition at the center of health. President Trump and Secretary Kennedy flipped the food pyramid to encourage Americans to Eat Real Food.

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      HHS is responsible for public health, health care, and human/social services for the United States of America. This includes administering over 100 programs and services.

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      HHS protects and helps you understand the laws and regulations, also known as "rules," that govern the nation. You also have the power to voice your opinion on these laws and regulations.

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      HHS gives the most money in grants of any federal agency in the U.S. Find out about our grants and how your organization can apply for them. We also provide information on how you can work with us and our support of small businesses.

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      HHS protects and helps you understand the laws and regulations, also known as "rules," that govern the nation. You also have the power to voice your opinion on these laws and regulations.

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  1. Home
  2. Grants and Contracts
  3. Grants
  4. Grants Policies & Regulations
  • HHS Grants
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    • Office of Grants and Acquisition Policy and Accountability

Grants Policies & Regulations

HHS grant applicants and recipients must follow government-wide requirements, HHS regulations, and the terms and conditions of their awards. Use this page to find the current HHS Grants Policy Statement and other key grants policies and regulations.

Help Protect the Integrity of HHS Grants!
If you suspect fraud, waste, or abuse related to HHS grant funding, please report it to the HHS Office of Inspector General (OIG)

HHS Grants Policy Statement

The HHS Grants Policy Statement (GPS) establishes the Department’s standard terms and conditions for grant awards and is incorporated by reference in the official Notice of Award. The GPS explains the legal and regulatory requirements governing HHS grants and provides Department-wide policy for award administration, post-award management, and oversight.

Current HHS Grants Policy Statement

Effective October 2025. This version supersedes all previous versions.

Read the HHS GPS online (webpage)

Download the HHS GPS

Previous versions are provided for historical reference. The applicable version may depend on the terms and effective date of an individual award.

  • HHS Grants Policy Statement (July 2025)
  • HHS Grants Policy Statement (April 2025)
  • HHS Grants Policy Statement (October 2024)
  • HHS Grants Policy Statement (Page I 29) (January 2007)

Government-wide Requirements

These resources establish government-wide requirements that apply across federal agencies.

  • Uniform Administrative Requirements, Cost Principles, and Audit Requirements for Federal Awards (Uniform Guidance)
    Government-wide requirements (2 CFR Part 200) governing the administration of federal financial assistance.
  • Council on Federal Financial Assistance (COFFA)
    COFFA coordinates federal grants management policy and government-wide initiatives.
  • Intergovernmental Review Guidance
    Guidance for State Single Points of Contact under Executive Order 12372.

HHS Regulations and Policies

These resources supplement government-wide requirements and provide HHS-specific policy implementation guidance.

  • HHS Adoption of the Uniform Guidance (2 CFR Part 300)
    HHS regulations implementing and supplementing the Uniform Guidance.
  • Financial Assistance General Certifications and Representations
    Required certifications and representations applicable to HHS financial assistance.
  • Build America. Buy America
    Requirements implementing domestic preference provisions applicable to eligible federal financial assistance.
  • Restrictions on Lobbying for Financial Assistance Recipients
    Requirements governing the use of federal funds for lobbying activities.
  • Writing Award Descriptions
    Guidance for drafting clear, consistent award descriptions.

For HHS Staff

The following resources are available for HHS personnel and support Department-wide implementation of grants policy.

  • Grants Policy Administration Manual (GPAM)
  • Action Transmittals
  • Grants Resource Hub
Content last reviewed September 4, 2026
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