Sexually Transmitted Infections (STIs)

In the United States, recent data show that rates of sexually transmitted infections (STIs) reached an all-time high in 2021 among both females and males, and all racial and ethnic groups. According to the Centers for Disease Control and Prevention (CDC), the number of combined cases of gonorrhea, syphilis and chlamydia was more than 2.4 million in 2023.While rates of gonorrhea and syphilis are slowing, reported STIs remain high and racial, ethnic, and sexual minority groups remain disproportionately affected.

The current rise of STIs is a serious public health concern that requires immediate attention. If left untreated, STIs can lead to severe health complications, including pelvic inflammatory disease (PID), increased risk of getting HIV, certain cancers, and even infertility.

The Office of the Assistant Secretary for Health (OASH) through the Office of Infectious Disease and HIV/AIDS Policy (OIDP) has coordinated, along with other federal agencies, the development of an inaugural STI National Strategic Plan (STI Plan). Stakeholders and the public had significant input into the development of this plan, through a variety of opportunities for public comment. The STI National Strategic Plan was released December 17, 2020, and provides a roadmap for prevention, diagnosis, treatment and care designed to meet significant measurable goals. The aim is for federal agencies and stakeholders to work together to reverse the alarming increase in STI rates and improve our nation’s health. The National Strategic Plan 2021-2023 Progress Report was released in November 2024 and provides an overview of federal progress on action steps but forward in the STI National Strategic Plan.

OIDP will continue to lead coordination of federal implementation of the STI Plan. Other stakeholders are encouraged to develop implementation plans for STI-related issues within their purview. Learn more about the STI Federal Implementation Plan*.

Additional Resources

Read the STI Plan and learn more about it.

*People using assistive technology may not be able to fully access information in these files. For assistance, contact the HHS Office of Infectious Disease and HIV/AIDS Policy by emailing Ann.Aikin@hhs.gov.