Key Strategies to Enhance Infection Prevention and Antibiotic Stewardship: Report with Recommendations for Human and Animal Health Image Access the Recommendation Report Key Strategies to Enhance Infection Prevention and Antibiotic Stewardship: Report with Recommendations for Human and Animal Health* Executive Summary Infection prevention and antibiotic stewardship (IP&AS) are essential to preventing and controlling infections, and to ensuring the prudent use of antibiotics. This report presents a set of key strategies to enhance IP&AS in human and animal health settings. The report identifies a number of gaps in IP&AS practices, including: lack of awareness of the importance of IP&AS among healthcare providers and animal health professionals, inadequate resources to implement IP&AS programs, and lack of coordination between human and animal health sectors. The report makes a number of recommendations to address these gaps, focused on improving federal support, implementation strategies, supporting science-based research, expanding the workforce and increasing IP&AS education and competencies. The effective and efficient implementation of IP&AS in a wide variety of settings would ultimately drive the growth and maintenance of a workforce with robust education and competencies at multiple levels to carry out the needed work to combat antibiotic-resistant infections and promote antibiotic stewardship. Associated PACCARB Working Group This report was compiled by Infection Prevention and Stewardship Working Group, and was voted on and approved by the full council at the 10th PACCARB Public Meeting on September 26, 2018. This working group was established in response to a Task Letter from U.S. Department of Health and Human Services Secretary of Health and Human Services, Alex M. Azar, II. *People using assistive technology may not be able to fully access information in these files. For assistance, contact the Presidential Advisory Council on Combating Antibiotic-Resistant Bacteria by emailing CARB@hhs.gov.