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Childhood Immunization Schedule by Recommendation Group

Immunizations Recommended for All Children

Childhood immunization schedule
Vaccine and other immunizing agentsBirth1 mo2 mos4 mos6 mos7 mos8 mos12 mos15 mos18 mos19 mos20-23 mos2-3 yrs4-6 yrs7 yrs8 yrs9 yrs10 yrs11 yrs12 yrs13 yrs14 yrs15 yrs16 yrs17 yrs
Diphtheria, tetanus, acellular pertussis (DTaP < 7 yrs)  
1st dose
2nd dose
3rd dose
   
4th dose
   
5th dose
           
Tetanus, diphtheria, acellular pertussis (Tdap ≥ 7 yrs)                  
1st dose
     
Haemophilus influenzae type b (Hib)  
1st dose
2nd dose
3rd dose
  
3rd/4th dose
                
Pneumococcal conjugate (PCV15, PCV20)  
1st dose
2nd dose
3rd dose
  
4th dose
                
Inactivated poliovirus (IPV < 18 yrs)  
1st dose
2nd dose
3rd dose
   
4th dose
           
Measles, mumps, rubella (MMR)       
1st dose
    
2nd dose
           
Varicella (VAR)       
1st dose
    
2nd dose
           
Human papillomavirus (HPV)                  
1st dose
     
Yellow lines = Some children should get this dose of vaccine at this age depending on their dose series 

Immunizations recommended for Certain High-Risk Groups or Populations

Childhood immunization schedule
Vaccine and other immunizing agentsBirth1 mo2 mos4 mos6 mos7 mos8 mos12 mos15 mos18 mos19 mos20-23 mos2-3 yrs4-6 yrs7 yrs8 yrs9 yrs10 yrs11 yrs12 yrs13 yrs14 yrs15 yrs16 yrs17 yrs
Respiratory syncytial virus (RSV-mAb)1
 1 dose
                   
Respiratory syncytial virus (RSV-mAb)2
 1 dose
 2nd dose
              
Hepatitis B (HepB)3
1st dose
2nd dose
 
3rd dose
               
Dengue4                
3 dose series
 
Meningococcal ACWY5  
2, 3, or 4 doses series
       
Meningococcal B6                 
1 dose
Hepatitis A (HepA)7    
1 dose
1 All children whose mother did not have the vaccine should get one dose.
2 High-risk children, such as those with chronic lung disease, should receive a second dose at ages 8 to 19 months.
3 Vaccination recommended for infants born to women who tested positive for the hepatitis B virus or whose status is unknown.
4 Recommended ONLY if living in areas with endemic dengue AND with a laboratory confirmation of previous dengue infection.
5 For high-risk groups (e.g., those with anatomic or functional asplenia or HIV infection), those traveling to countries with hyperendemic or epidemic meningococcal disease, and first-year college students living in residential housing, vaccination is recommended.
6 Recommended for high-risk groups, e.g., with anatomic or functional asplenia, and during outbreaks.
7 Vaccination recommended for international travel to areas with high or intermediate hepatitis A endemicity.

Immunizations Based on Shared Clinical Decision-Making

Childhood immunization schedule
Vaccine and other immunizing agentsBirth1 mo2 mos4 mos6 mos7 mos8 mos12 mos15 mos18 mos19 mos20-23 mos2-3 yrs4-6 yrs7 yrs8 yrs9 yrs10 yrs11 yrs12 yrs13 yrs14 yrs15 yrs16 yrs17 yrs
Rotavirus (RV): RV1 (2-dose series), RV5 (3-dose series)  
1st dose
2nd dose
3rd dose
                    
COVID-19 (1vCOV-mRNA, 1vCOV-aPS)    
2 doses first year, then 1 dose annually
1 dose annually
Influenza (IIV3, ccIIV3)    
2 doses first year, then 1 dose annually
1 dose annually
Influenza (LAIV3)            
2 doses first year, then 1 dose annually
1 dose annually
Hepatitis A (HepA)       
2-dose series
             
Hepatitis B (HepB)*  
1st dose
2nd dose
3rd dose
               
Meningococcal ACWY                  
1st dose
   
2nd dose
 
Meningococcal B                       
2 or 3 doses
Blue lines = Some children should get this dose of vaccine at this age depending on their dose series
* For parents deciding whether to vaccinate for HepB in infants born to women who tested negative for the hepatitis B virus, it is suggested that the initial dose is administered no earlier than 2 months of age.

What diseases do these vaccines protect against?

Vaccine-Preventable DiseaseDisease Complications
Diphtheria
Illness caused by a toxin produced by bacteria that infects the nose, throat, and sometimes skin.
Swelling of the heart muscle, heart failure, coma, paralysis, death
Tetanus (Lockjaw)
Bacterial infection of brain and nerves caused by spores found in soil and dust everywhere; spores enter the body through wounds or broken skin
Seizures, broken bones, difficulty breathing, death
Pertussis (Whooping Cough)
Contagious bacterial infection of the lungs and airway; spread through air and direct contact
Infection of the lungs (pneumonia), death; especially dangerous for babies
Hib (Haemophilus influenzae type b)
Contagious bacterial infection of the lungs, brain and spinal cord, or bloodstream; spread through air and direct contact
Depends on the part of the body infected, but can include brain damage, hearing loss, loss of arm or leg, death
Pneumococcal
Bacterial infections of ears, sinuses, lungs, or bloodstream; spread through direct contact with respiratory droplets like saliva or mucus
Depends on the part of the body infected, but can include infection of the lungs (pneumonia), blood poisoning, infection of the lining of the brain and spinal cord, death
Polio
Contagious viral infection of nerves and brain; spread through the mouth from stool on contaminated hands, food or liquid, and by air and direct contact
Paralysis, death
Measles (Rubeola)
Contagious viral infection that causes high fever, cough, red eyes, runny nose, and rash; spread through air and direct contact
Brain swelling, infection of the lungs (pneumonia), death
Mumps
Contagious viral infection that causes fever, tiredness, swollen cheeks, and tender swollen jaw; spread through air and direct contact
Brain swelling, painful and swollen testicles or ovaries, deafness, death
Rubella (German Measles)
Contagious viral infection that causes low-grade fever, sore throat, and rash; spread through air and direct contact
Very dangerous in pregnant women; can cause miscarriage or stillbirth, premature delivery, severe birth defects
Chickenpox (Varicella)
Contagious viral infection that causes fever, headache, and an itchy, blistering rash; spread through air and direct contact
Infected sores, brain swelling, infection of the lungs (pneumonia), death
HPV (Human papillomavirus)
Contagious viral infection spread by close skin-to-skin touching, including during sex
Genital warts and many types of cancers later in life, including cancers of the cervix, vagina, penis, anus, and throat
RSV (Respiratory syncytial virus)
Contagious viral infection of the nose, throat, and sometimes lungs; spread through air and direct contact
Infection of the lungs (pneumonia) and small airways of the lungs; especially dangerous for infants and young children
Hepatitis B
Contagious viral infection of the liver; spread through contact with infected body fluids such as blood or semen
Chronic liver infection, liver failure, liver cancer, death
Dengue
Viral infection spread by bite from infected mosquito; causes, fever, headache, pain behind the eyes, rash, joint pain, body ache, nausea, loss of appetite, feeling tired, abdominal pain
Severe bleeding, seizures, shock, damage to the liver, heart, and lungs, death
Mpox
Contagious viral infection spread through close, often skin-to-skin contact, including sex; causes a painful rash, fever, headache, tiredness, cough, runny nose, sore throat, swollen lymph nodes
Infected sores, brain swelling, infection of the lungs (pneumonia), eye infection, blindness, death
Meningococcal
Contagious bacterial infection of the lining of the brain and spinal cord or the bloodstream; spread through air and direct contact
Loss of arm or leg, deafness, seizures, death
Rotavirus
Contagious viral infection of the gut; spread through the mouth from hands and food contaminated with stool
Severe diarrhea, dehydration, death
COVID-19
Contagious viral infection of the nose, throat, or lungs; may feel like a cold or flu. Spread through air and direct contact
Infection of the lungs (pneumonia); blood clots; liver, heart or kidney damage; long COVID; death
Influenza (Flu)
Contagious viral infection of the nose, throat, and sometimes lungs; spread through air and direct contact
Infection of the lungs (pneumonia), sinus and ear infections, worsening of underlying heart or lung conditions, death
Hepatitis A
Contagious viral infection of the liver; spread by contaminated food or drink or close contact with an infected person
Liver failure, death
Content created by Assistant Secretary for Public Affairs (ASPA)
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