An estimated 4.4 million Americans from all walks of life are living with viral hepatitis. Most people with chronic hepatitis B virus (HBV) or hepatitis C virus (HCV) don’t have symptoms until the later stages of the infection. As a result, many Americans living with viral hepatitis do not know they are infected and are at risk for serious liver disease, liver cancer, and even death. The numbers of new HBV and HCV infections and viral hepatitis-related deaths have increased in recent years. As a nation, we are at risk of losing ground in the battle against these “silent epidemics.” But, today, we have more knowledge and tools than ever before to stop the spread of viral hepatitis and save lives. To harness these tools and focus our national response to viral hepatitis, the Action Plan for the Prevention, Care & Treatment of Viral Hepatitis coordinates and leverages the efforts of 21 federal partners in fighting viral hepatitis across the United States. It also supports and encourages the complementary efforts of a wide range of partners outside the federal government, including states, counties, cities and hundreds of organizations and individuals engaged in the fight against hepatitis B and C.