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- Assistant Secretary
(Loyce Pace)- Principal Deputy Assistant Secretary
(Susan Kim)
- Chief of Staff
(Michael Beard)
- Chief Advisor for Policy and Strategy
(Caya Lewis Atkins)
- Deputy Assistant Secretary
(Colin McIff)
- Policy and Program Coordination
- Agency Coordination
- Executive Operations Office
- Multilateral Affairs
- Pandemics and Emerging Threats
- PEPFAR
- Trade and Health
- USMBHC
- Regional Offices
- Africa Office
- Americas Office
- Asia Pacific Office
- Europe Eurasia Office
- Middle East Office
- Principal Deputy Assistant Secretary