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OPT Billing Payment Overview

Guidance for This guidance provides new OPT billing information for CY 2021.


Issued by: Centers for Medicare & Medicaid Services (CMS)

New covered services include FDA-approved opioid antagonist medications, specifically naloxone, for emergency treatment of opioid overdose, as well as overdose education

  • New codes for nasal and injectable naloxone
  • OTPs may conduct periodic assessments via two-way interactive audio-video communication technology
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    DISCLAIMER: The contents of this database lack the force and effect of law, except as authorized by law (including Medicare Advantage Rate Announcements and Advance Notices) or as specifically incorporated into a contract. The Department may not cite, use, or rely on any guidance that is not posted on the guidance repository, except to establish historical facts.