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Accelerate the Process of Scientific Discovery to Improve Health

The path from basic scientific discovery to methods and technologies that improve patient care can be lengthy and complex.  HHS is committed to promoting faster translation of research into practice, and ensuring that it meets the varying needs of diverse communities in culturally and linguistically appropriate ways.  Accelerating this process can help HHS meet its goals, including promoting high-value, safe, and effective health care, eliminating health disparities, supporting informed decision-making, and ultimately, improving health outcomes.

Accelerate Biomedical and Behavioral Sciences Discovery through Innovation

HHS is accelerating biomedical discovery through innovative methodologies and technology.  HHS will continue to support fundamental discoveries that expand the knowledge base in the biomedical and behavioral sciences.  HHS is accelerating scientific discovery by promoting ongoing cross-agency development of information systems capable of storing, organizing, and sharing vast amounts of data with researchers around the globe.

Enable Efficient Regulatory Review

HHS is facilitating the fast-tracking of medical innovations to integrate biomedical research planning and regulatory review.  HHS is supporting training of regulatory scientists to develop the skills necessary to integrate research planning and the regulation of resulting biomedical products.  HHS is developing cross-agency initiatives to support regulatory science to enhance the safety, quality, and efficiency of clinical research and medical product approval.

Translate Novel Research Discoveries into Therapies

HHS is exploring new partnerships that can help academic investigators translate basic science into new therapies with the potential for commercial development.  HHS is providing researchers with large-scale screening resources to facilitate identification of small molecules that may have a beneficial effect against a disease target.  HHS also is providing resources for preclinical evaluation of promising therapeutics, and is building a national network of clinical research centers to enable clinical trials of promising compounds.

Support the Science of Health Care Reform

HHS supports patient-centered research to identify high-quality, high-value drugs, medical devices, surgeries, and other treatment options.  HHS supports research on personalized medicine, population health, behavioral science, health economics, health disparities, and health services.  Health services research is important to ensure the best evidence is used to improve health care delivery.  By examining and enhancing the most effective ways to integrate preventive, screening, diagnostic, and treatment health services into community practice, HHS further supports more effective individualized prevention efforts, as well as methods to deliver the right care to the right patient at the right time, regardless of race, ethnicity or socioeconomic status.

Accelerate Understanding of Brain Function

HHS is investing in an accelerated effort to map and understand brain function through the Brain Research through Application of Innovative Neurotechnologies (BRAIN) Initiative.  The initiative will map the dynamic nature of the brain and help identify differences in normal and abnormal function. This will advance an understanding of neurological and psychiatric disorders, such as Alzheimer’s disease, Parkinson’s disease, autism, epilepsy, schizophrenia, depression, and traumatic brain injury.

Support the Science of Community Prevention

HHS supports community-based research to identify prevention strategies that protect health and prevent diseases.  Research is conducted to expand understanding of the most effective and affordable strategies to promote health, including changes to the community, worksite, and school environment, the role of media, policy, pricing, and other means of making the healthy choice easy and affordable.  Research also is expanding understanding of the role of other sectors on health such as transportation, education, and housing.

Disseminate Health Information to the Public

HHS is developing a comprehensive plan to disseminate health information to the public more effectively.  HHS is carefully examining the effectiveness of information tailored to underserved populations, which often have greater risk of certain diseases and conditions. HHS is working to develop public-private partnerships with industry, professional medical groups, health insurance providers, state and local health departments, and other stakeholders to leverage its efforts to inform and care for underserved populations.