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HHS Federal Program Inventory

National Institutes of Health (NIH)

Budget Authority (in millions of dollars)

 FY 2012FY 2013FY 2014
Discretionary30,70230,89931,173
Mandatory150150150

 

5.1    National Library of Medicine

The National Library of Medicine (NLM), on the campus of the NIH in Bethesda, MD, has been a center of information innovation since its founding in 1836.  The world’s largest biomedical library, NLM maintains and makes available a vast print collection and produces electronic information resources on a wide range of topics that are searched billions of times each year by millions of people around the globe.  It also supports and conducts research, development, and training in biomedical informatics and health information technology.  In addition, the Library coordinates a 6,000-member National Network of Libraries of Medicine that promotes and provides access to health information in communities across the United States.

  • Supported Strategic Goal:  Advance scientific knowledge and innovation
  • Supported Strategic Objective:  Accelerate the process of scientific discovery to improve patient care

5.2    John E. Fogarty International Center

The Fogarty International Center is dedicated to advancing the mission of the NIH by supporting and facilitating global health research conducted by U.S. and international investigators, building partnerships between health research institutions in the U.S. and abroad and training the next generation of scientists to address global health needs.  The Center works to address the growing epidemic of chronic non-communicable diseases across the globe, strengthen capacity to reduce the burden of infectious diseases, bridge the implementation research training gap, develop human capital in the developing world, foster a sustainable research environment in low- and middle-income countries, and build strategic alliances and partnerships between researchers and institutions in the U.S. and other countries..

  • Supported Strategic Goal:  Advance scientific knowledge and innovation
  • Supported Strategic Objective:  Accelerate the process of scientific discovery to improve patient care

5.3    Buildings and Facilities at NIH

The NIH Office of Research Facilities (ORF) supports the NIH mission by providing, maintaining, and operating safe, healthy, and attractive facilities.  ORF operates as a “central service” and reports directly to the Office of Management, located within the Office of the Director of the NIH.  ORF services are funded through a census-based Management Fund assessment, rent, membership fees, and fee‑for‑service direct charges.  In addition, direct appropriations for Buildings and Facilities support the Construction, Essential Safety and Regulatory Compliance, and Repairs and Improvements Programs.

  • Supported Strategic Goal:  Increase efficiency, transparency and accountability of HHS programs
  • Supported Strategic Objective:  Ensure program integrity and responsible stewardship of resources

5.4    Aging Research

The National Institute on Aging (NIA) leads a national scientific effort to understand the nature of aging in order to promote the health and well-being of older adults.  NIA’s mission is to support and conduct genetic, biological, clinical, behavioral, social, and economic research related to the aging process, diseases and conditions associated with aging, and other special problems and needs of older Americans; foster the development of research and clinician-scientists for research on aging; and communicate information about aging and advances in research on aging with the scientific community, health care providers, and the public. NIA is also the lead federal agency for Alzheimer’s disease research. The NIA mission is carried out by supporting extramural research at universities, research centers, and medical centers across the United States and around the world, as well as a vibrant intramural research program at NIA laboratories in Baltimore and Bethesda, Maryland.

  • Supported Strategic Goal:  Advance scientific knowledge and innovation
  • Supported Strategic Objective:  Accelerate the process of scientific discovery to improve patient care

5.5    Child Health and Human Development Research

In 2012, the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) celebrated 50 years of scientific achievements.  Its anniversary theme, “Research for a Lifetime,” highlighted the far-ranging impact of its mission:  to ensure that every person is born healthy and wanted, that women suffer no harmful effects from reproductive processes, that all children have the chance to achieve their full potential for healthy and productive lives; and to ensure the health, productivity, independence, and well-being of all people through optimal rehabilitation.  NICHD research is uniquely positioned to advance understanding of the basic mechanisms that transform cells into healthy and functioning individuals, while our translational studies help improve the lifelong health and well-being of women, children, and individuals with disabilities.

  • Supported Strategic Goal:  Advance scientific knowledge and innovation
  • Supported Strategic Objective:  Accelerate the process of scientific discovery to improve patient care

5.6    NIH Program Support and Crosscutting Research Projects

The NIH Program Support and Crosscutting Research Projects program is responsible for setting policy for NIH and for planning, managing, and coordinating the programs and activities of all the NIH components. The program provides overall leadership to NIH activities in both scientific and administrative matters. Funding is appropriated through the budget of the Office of the NIH Director (OD).   This program supports the efforts of the OD Offices of Extramural Research, Intramural Research, Science Policy, Management, Communications and Public Liaison, Legislative Policy and Analysis, and Equity Diversity and Inclusion, as well as the Center for Scientific Review and the Center for Information Technology.   

The program focuses on implementing the following themes across the NIH:

  1. Today’s Basic Science for Tomorrow’s Breakthroughs
  2. Translational Science
  3. Recruiting and Retaining Diverse Scientific Talent and Creativity
  4. Restoring American Competitiveness

In addition, through the OD Division of Coordination, Planning, and Strategic Initiatives, the program is responsible for stimulating specific areas of research throughout NIH and for planning and supporting research and related activities, including women's health, AIDS research, disease prevention, and behavioral and social sciences research.

  • Supported Strategic Goal:  Advance scientific knowledge and innovation
  • Supported Strategic Objective:  Accelerate the process of scientific discovery to improve patient care

5.7    Cancer Research

The National Cancer Institute (NCI) has produced a current landscape of unmatched promise in the oncological sciences, arriving at a time when the world of cancer research has expanded in talent, facilities, and ideas.  Progress in molecular biology, especially in the deciphering of cancer genomes and the probing of the signaling pathways that govern normal and malignant cell growth, has transformed our ability to understand the broken parts of a cancer cell; develop new and more precise therapeutic strategies; reformulate diagnostic categories; and imagine screening for and prevention of some cancers in more powerful ways.  In just the past few years, NCI-supported science has delivered a remarkable collection of genetic information about several types of cancers, a number of new targeted therapies for various cancers, compelling examples of successful immunologically based therapies, persuasive evidence that radiographic screening can reduce lung cancer mortality, and many new observations about the genesis of cancer cells, their development, their behavior, and their microenvironment.

  • Supported Strategic Goal:  Advance scientific knowledge and innovation
  • Supported Strategic Objective:  Accelerate the process of scientific discovery to improve patient care

5.8    General Medical Sciences Research

The mission of the National Institute of General Medical Sciences (NIGMS) is to support research that increases understanding of life processes and lays the foundation for advances in disease diagnosis, treatment and prevention. NIGMS-funded researchers seek to answer important scientific questions in fields such as cell biology, biophysics, genetics, developmental biology, pharmacology, physiology, biological chemistry, biomedical technology, bioinformatics, computational biology, selected aspects of the behavioral sciences, and specific cross-cutting clinical areas that affect multiple organ systems. To assure the vitality and continued productivity of the research enterprise, NIGMS also provides leadership in training the next generation of scientists as well as in developing and increasing the diversity of the scientific workforce.

  • Supported Strategic Goal:  Advance scientific knowledge and innovation
  • Supported Strategic Objective:   Accelerate the process of scientific discovery to improve patient care

5.9    Environmental Health Sciences Research

The mission of the National Institute of Environmental Health Sciences (NIEHS is to discover how the environment affects people; this knowledge is then leveraged to promote healthier lives.  The NIEHS traces its roots to 1966, when the U.S. Surgeon General announced the establishment of the Division of Environmental Health Sciences within the NIH.  In 1969, the division was elevated to full NIH Institute status.  Since then, the NIEHS has evolved to its present status as a world leader in environmental health sciences, with an impressive record of important scientific accomplishments and a proud history of institutional achievements and growth.  Researchers investigate biostatistics, epidemiology, molecular carcinogenesis, molecular genetics, neurobiology, reproductive and developmental toxicology, respiratory biology, signal transduction, and toxicology and pharmacology.

  • Supported Strategic Goal:  Advance scientific knowledge and innovation
  • Supported Strategic Objective:  Accelerate the process of scientific discovery to improve patient care

5.10  Heart, Lung, and Blood Research

The National Heart, Lung, and Blood Institute (NHLBI) provides global leadership for research, training, and education programs to prevent and treat heart, lung, and blood diseases and enhance the health of all individuals so that they can live longer and more fulfilling lives.

The NHLBI stimulates basic discoveries about the causes of disease, enables the translation of basic discoveries into clinical practice, fosters training and mentoring of emerging scientists and physicians, and communicates research advances to the public. It creates and supports a robust, collaborative research infrastructure in partnership with private and public organizations, including academic institutions, industry, and other government agencies. The Institute collaborates with patients, families, health care professionals, scientists, professional societies, patient advocacy groups, community organizations, and the media to promote the application of research results and leverage resources to address the health needs of the public. The NHLBI also collaborates with international organizations to help reduce the burden of heart, lung, and blood diseases worldwide

  • Supported Strategic Goal:  Advance scientific knowledge and innovation
  • Supported Strategic Objective:  Accelerate the process of scientific discovery to improve patient care

5.11  Dental and Craniofacial Research

The National Institute of Dental and Craniofacial Research (NIDCR) is the largest institution in the world dedicated exclusively to the improvement of dental, oral, and craniofacial health.  Founded in 1948, NIDCR supports scientists using modern biomedical research tools to conduct research on the full spectrum of topics related to diseases and conditions that fall within NIDCR's mission.  This research includes:  investigations into the biochemistry, structure, function, and development of bone, teeth, salivary glands, connective tissues, and the immune system; studies that focus on the role of bacteria and viruses in oral disease; genetic and acquired disorders of the craniofacial region and tumors of the oral cavity; the causes and treatment of acute and chronic pain; and the development of new and improved methods to diagnose oral disease.  NIDCR also supports research to improve the oral health of diverse underserved populations, and to understand both the mechanisms of behavior change and the influence of behavioral and social factors on oral health.  Beyond basic and clinical research, NIDCR also supports research training and career development programs to ensure an adequate number of talented, well-prepared, and diverse investigators; coordinates and assists relevant research activities among all sectors of the research community; and promotes the timely transfer of new research findings to the public, health professionals, researchers, and policy-makers.

  • Supported Strategic Goal:  Advance scientific knowledge and innovation
  • Supported Strategic Objective:  Accelerate the process of scientific discovery to improve patient care

5.12  Diabetes and Digestive and Kidney Disease Research

The mission of the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) is to conduct and support medical research and research training and to disseminate science-based information on diabetes and other endocrine and metabolic diseases; digestive diseases, nutritional disorders, and obesity; and kidney, urologic, and hematologic diseases, to improve people’s health and quality of life.  The NIDDK supports a wide range of medical research through grants to universities and other medical research institutions across the country. The Institute also supports government scientists who conduct basic, translational, and clinical research across a broad spectrum of research topics and serious, chronic diseases and conditions related to the Institute's mission. In addition, the NIDDK supports research training for students and scientists at various stages of their careers and a range of education and outreach programs to bring science-based information to patients and their families, health care professionals, and the public.

  • Supported Strategic Goal:  Advance scientific knowledge and innovation
  • Supported Strategic Objective:  Accelerate the process of scientific discovery to improve patient care

5.13  Allergy and Infectious Diseases Research

The National Institute of Allergy and Infectious Diseases (NIAID) conducts and supports basic and applied research to better understand, treat, and ultimately prevent infectious, immunologic, and allergic diseases. For more than 60 years, NIAID research has led to new therapies, vaccines and vaccine adjuvants that boost vaccine effectiveness, diagnostic tests, and other technologies that have improved the health of millions of people in the United States and around the world. Among the 27 Institutes and Centers that comprise the National Institutes of Health (NIH), NIAID has a unique mandate, which requires the Institute to respond to emerging public health threats. Toward this end, NIAID manages a complex and diverse research portfolio that aims to do the following:

  • Expand the breadth and depth of knowledge in all areas of infectious, immunologic, and allergic diseases
  • Advance the development of new and better diagnostics, vaccines, drugs, and other treatments for infectious and immune-mediated diseases
  • Develop flexible research capacities to respond appropriately to emerging and re-emerging disease threats

Key NIAID research areas include newly emerging and re-emerging infectious diseases such as tuberculosis (TB), malaria, and influenza; antimicrobial resistance; HIV/AIDS; and biodefense. The Institute’s top scientific priorities include development of a universal influenza vaccine, HIV prevention strategies including vaccines, study of human immunology, and development of medical interventions for immune-mediated diseases including asthma and allergy.

  • Supported Strategic Goal:  Advance scientific knowledge and innovation
  • Supported Strategic Objective:  Accelerate the process of scientific discovery to improve patient care

5.14  Neurological Disorders and Stroke Research

The mission of the National Institute of Neurological Disorders and Stroke (NINDS) is to reduce the burden of neurological disorders through research. Hundreds of disorders, both common and rare, affect the nervous system. Together, these diseases afflict people of all ages, cause an enormous burden in lost life, disability, and suffering, and cost billions of dollars each year in medical expenses and reduced productivity. To support this mission, NINDS supports and conducts research on the causes, prevention, diagnosis, and treatment of neurological disorders and stroke, as well as basic research to better understand the nervous system and its functions.  This research includes studies conducted with grant or contract support to public and private institutions, and a diversified program of intramural and collaborative research in laboratories on the NIH campus in Bethesda, Maryland. NINDS also disseminates research information related to neurological disorders to practitioners, researchers, and the public.

  • Supported Strategic Goal:  Advance scientific knowledge and innovation
  • Supported Strategic Objective:  Accelerate the process of scientific discovery to improve patient care

5.15  Eye Research

Blinding eye diseases, such as age-related macular degeneration, diabetic retinopathy, and glaucoma affect millions of Americans of all ages and ethnicities.  These and other visual disorders derail productive careers, rob people of their mobility and independence, and add to the economic burden of health care.  The mission of the National Eye Institute (NEI) is to "conduct and support research, training, health information dissemination, and other programs with respect to blinding eye diseases, visual disorders, mechanisms of visual function, preservation of sight, and the special health problems and requirements of the blind."  NEI supports research programs on retinal diseases; corneal diseases; lens and cataract; glaucoma and optic neuropathies; strabismus, amblyopia, and visual processing; low vision and blindness rehabilitation; myopia and and refractive error; ocular infection, inflammation, and immunology; oculomotor systems and neuro-ophthalmology; and ocular pain. In support of its mission, NEI funds over 1,400 research grants and training awards made to scientists at more than 250 medical centers, hospitals, and universities across the country and around the world.  NEI also conducts laboratory and patient-oriented research at its own facilities located on the NIH campus in Bethesda, Maryland.

  • Supported Strategic Goal:  Advance scientific knowledge and innovation
  • Supported Strategic Objective:  Accelerate the process of scientific discovery to improve patient care

5.16  Arthritis and Musculoskeletal and Skin Diseases Research

As the primary federal agency for supporting medical research on diseases of the bones, joints, muscles, and skin, the National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) touches the lives of nearly every American. The burden of these diseases is substantial.  Arthritis limits the activities of nearly 21 million adults in the United States each year; medical care and lost wages attributable to musculoskeletal conditions cost Americans an estimated $950 billion annually; and skin conditions such as eczema and psoriasis affect more than 12 percent of people world-wide.  NIAMS is accomplishing its mission of improving health by supporting basic and translational research that will impact clinical practice, by training the next generation of bone, joint, muscle, and skin scientists, and by disseminating the findings from its studies, and related health information, to all Americans. 

  • Supported Strategic Goal:  Advance scientific knowledge and innovation
  • Supported Strategic Objective:  Accelerate the process of scientific discovery to improve patient care

5.17  Nursing Research

The mission of the National Institute of Nursing Research (NINR) is to promote and improve the health of individuals, families, communities, and populations. The Institute supports and conducts clinical and basic research and research training on health and illness across the lifespan to build the scientific foundation for clinical practice, prevent disease and disability, manage and eliminate symptoms caused by illness, and improve palliative and end-of-life care.  NINR also supports the training of new investigators who bring new ideas and help to further expand research programs. The ultimate goal of NINR research is its dissemination into clinical practice and into the daily lives of individuals and families.

  • Supported Strategic Goal:  Advance scientific knowledge and innovation
  • Supported Strategic Objective:  Accelerate the process of scientific discovery to improve patient care

5.18  Deafness and Other Communication Disorders Research

Established in 1988, the National Institute on Deafness and Other Communication Disorders (NIDCD) is mandated to conduct and support biomedical and behavioral research and research training in the normal and disordered processes of hearing, balance, taste, smell, voice, speech, and language. The Institute also conducts and supports research and research training related to disease prevention and health promotion; addresses special biomedical and behavioral problems associated with people who have communication impairments or disorders; and supports efforts to create devices which substitute for lost and impaired sensory and communication function.

It is estimated that more than 46 million people in the United States suffer some form of disordered communication. NIDCD has focused national attention on disorders of human communication and has contributed to advances in biomedical and behavioral research that will improve the lives of millions of individuals with communication disorders. NIDCD has made important contributions to the body of knowledge needed to help those who experience communication disorders and to advance research in all aspects of human communication.

  • Supported Strategic Goal:  Advance scientific knowledge and innovation
  • Supported Strategic Objective:  Accelerate the process of scientific discovery to improve patient care

5.19  Human Genome Research

In the decade since the completion of the Human Genome Project (HGP), genomics has become central to biomedical research, with remarkable genomic accomplishments seen across myriad disciplines.  The research funded by the National Human Genome Research Institute (NHGRI) has catalyzed a transformation in how biomedical science is conducted, and genomic tools and strategies are now advancing toward clinical integration and the realization of genomic medicine. Genomic analyses increasingly shed light on fundamental knowledge about biology and its perturbation in disease.  NHGRI’s leadership in high-throughput strategies and technology development continues to stimulate progress and innovation in basic and translational research, which in turn will enable the breakthroughs that will improve health outcomes for the nation.

In February 2011, NHGRI published a new strategic vision for genomics research.  This updated vision articulates five research domains that together comprise a progressive continuum leading to the realization of genomics-informed medicine, namely understanding the structure of genomes; understanding the biology of genomes; understanding the biology of disease; advancing the science of medicine; and improving the effectiveness of healthcare. 

  • Supported Strategic Goal:  Advance scientific knowledge and innovation
  • Supported Strategic Objective:  Accelerate the process of scientific discovery to improve patient care

5.20  Mental Health Research

The National Institute of Mental Health (NIMH) is the lead federal agency for research on mental and behavioral disorders, with a mission to transform the understanding and treatment of mental illnesses through basic and clinical research, paving the way for prevention, recovery, and cure.  In a given year, an estimated 11.4 million American adults (approximately five percent of all adults) suffer from a seriously disabling mental illness.  Mental disorders are the leading cause of disability in the United States and Canada, accounting for 28 percent of all years of life lost to disability and premature mortality (Disability Adjusted Life Years or DALYs).  The social and economic costs associated with these disorders are tremendous, at well over $300 billion annually. 

Schizophrenia, bipolar disorder, depression, post-traumatic stress disorder, anxiety disorders, autism spectrum disorder, eating disorders, borderline personality disorder, and other disorders are seriously disabling, life-threatening illnesses.  NIMH’s Strategic Plan provides direction for harnessing rigorous scientific research to develop new diagnostic tests, more effective interventions, and better prevention strategies to address the public health burden of these disorders. 

  • Supported Strategic Goal:  Advance scientific knowledge and innovation
  • Supported Strategic Objective:  Accelerate the process of scientific discovery to improve patient care

5.21  Drug Abuse Research

The National Institute on Drug Abuse (NIDA)’s mission is to lead the nation in bringing the power of science to bear on drug abuse and addiction.  This charge has two critical components.  The first is the strategic support and conduct of research across a broad range of disciplines.  The second is ensuring the rapid and effective dissemination and use of the results of that research to significantly improve prevention and treatment and to inform policy as it relates to drug abuse and addiction.

  • Supported Strategic Goal:  Advance scientific knowledge and innovation
  • Supported Strategic Objective:  Accelerate the process of scientific discovery to improve patient care

5.22  Alcohol Abuse and Alcoholism Research

The National Institute on Alcohol Abuse and Alcoholism (NIAAA) supports and conducts research on the impact of alcohol use on human health and well-being. It is the largest funder of alcohol research in the world.  Through this research, NIAAA aims to better understand the health risks and benefits of consuming alcohol, as well as why it can cause addiction, reveal the biological and socio-cultural origins of why people respond to alcohol differently, remove the stigma associated with alcohol problems, and develop effective prevention and treatment strategies that address the physical, behavioral, and social risks.

  • Supported Strategic Goal:  Advance scientific knowledge and innovation
  • Supported Strategic Objective:  Accelerate the process of scientific discovery to improve patient care

5.23  AIDS Policy and Budget

The Office of AIDS Research (OAR) coordinates the scientific, budgetary, legislative, and policy elements of NIH AIDS research. The NIH represents the largest and most significant public investment in AIDS research in the world. Our response to the epidemic requires a unique and complex multi-institute, multi-disciplinary, global research program. Perhaps no other disease so thoroughly transcends every area of clinical medicine and basic scientific investigation, crossing the boundaries of nearly every Institute and Center. This diverse research portfolio demands an unprecedented level of scientific coordination and management of research funds to identify the highest priority areas of scientific opportunity, enhance collaboration, minimize duplication, and ensure that precious research dollars are invested effectively and efficiently. OAR sets the trans-NIH scientific priorities for this large and diverse program, which is conducted or supported by nearly every NIH Institute and Center. Through its unique comprehensive trans-NIH planning, budgeting, and portfolio assessment processes, OAR is enhancing collaboration and ensuring that research dollars are invested in the highest priority areas of scientific opportunity that will lead to new tools in the global fight against AIDS.

  • Supported Strategic Goal:  Advance scientific knowledge and innovation
  • Supported Strategic Objective:  Accelerate the process of scientific discovery to improve patient care

5.24  Complementary and Alternative Medicine Research

The National Center for Complementary and Alternative Medicine (NCCAM) is the federal Government’s lead agency for scientific research on various complementary health interventions and their potential role in integrative strategies for treating difficult health conditions and promoting better health.  NCCAM is committed to building the scientific evidence needed by consumers, providers, and health policymakers regarding the safety and usefulness of these approaches to improve health and health care.

Nearly 40 percent of Americans are integrating complementary health interventions into their health care and personal health practices, at an annual cost of $34 billion dollars. While decisions about the use of these interventions are sometimes made with the guidance of a professional health care provider, this is often not the case.  Furthermore, both consumers and providers are often confronted with limited objective information about the safety and effectiveness of these approaches. To address these evidence gaps, NCCAM funds research across the continuum of basic, translational, and clinical research, guided by its strategic plan.

  • Supported Strategic Goal:  Advance scientific knowledge and innovation
  • Supported Strategic Objective:  Accelerate the process of scientific discovery to improve patient care

5.25  Minority Health and Health Disparities Research

The mission of the National Institute on Minority Health and Health Disparities (NIMHD) is to lead scientific research to improve minority health and eliminate health disparities.  Cognizant of the potential of science and the multiple factors and related issues that underlie health disparities, NIMHD’s approach to achieving its mission is embodied in building a broad-based coalition of partners across multiple disciplines and sectors.  Although the United States has seen recent improvements in the overall quality of care, stark disparities in quality and access to care persist in many communities, as well as pervasive differences in health between groups around the country.  Increasing evidence-based research findings continues to underscore the complex interplay of factors such as race, ethnicity, social, economic, geographic, environmental, genetic, and behavioral influences across the life-course that contributes to the early onset of disease, the aggressive progression of a disease, and to premature death.

The NIMHD’s emphasis and priorities to better understand minority health and health disparities are shaped by the emergence of new data from the field that present novel areas for opportunity and by the priorities of the NIH Director.  In particular, translational science and recruiting and retaining diverse scientific talent and creativity are foundational aspects of the Institute’s efforts to eliminate health disparities. The approach of health disparities programs is to examine the causes of health disparities; integrate science, practice, and policy approaches to address health disparities; provide a platform for academic institutions to conduct research and support the training of a diverse workforce; offer a vehicle to build community research capacity, study national and global patterns of health disparities; and advance the translation and dissemination of research results.

  • Supported Strategic Goal:  Advance scientific knowledge and innovation
  • Supported Strategic Objective:  Accelerate the process of scientific discovery to improve patient care

5.26  Biomedical Imaging and Bioengineering Research

The mission of the National Institute of Biomedical Imaging and Bioengineering (NIBIB) is to improve health by leading the development and accelerating the application of biomedical technologies. Th e Institute is committed to integrating the physical and engineering sciences with the life sciences to advance basic research and medical care. This is achieved through:  research and development of new biomedical imaging and bioengineering techniques and devices to fundamentally improve the detection, treatment, and prevention of disease; enhancing existing imaging and bioengineering modalities; supporting related research in the physical and mathematical sciences; encouraging research and development in multidisciplinary areas; supporting studies to assess the effectiveness and outcomes of new biologics, materials, processes, devices, and procedures; developing technologies for early disease detection and assessment of health status; and developing advanced imaging and engineering techniques for conducting biomedical research at multiple scales.  The Institute supports basic research and research training through investigator-initiated grants, contracts, program project and center grants, and career development and training awards.

  • Supported Strategic Goal:  Advance scientific knowledge and innovation
  • Supported Strategic Objective:  Accelerate the process of scientific discovery to improve patient care

5.27  Advancing Translational Sciences Research

The National Center for Advancing Translational Sciences (NCATS) was established in fiscal year 2012. NCATS catalyzes innovative methods and technologies that enhance the development, testing and clinical application of preventions and treatments to tangibly improve human health across a wide range of diseases and conditions.

Currently, the process of developing a new intervention is slow and expensive:  Approximately 7,000 diseases affect humans, yet fewer than 500 have any treatment. NCATS programs and initiatives help address this gap by taking basic discoveries about the causes of a disease and transforming this knowledge into a new treatment, such as a device, diagnostic, drug or behavioral intervention. NCATS emphasizes collaboration, innovation and deliverables, relying on the power of data and new technologies to develop, demonstrate and disseminate improvements in translational science.

In these ways, NCATS is serving as an adaptor to enable other parts of the research ecosystem to work more effectively, and complementing — not competing with — the work of other NIH Institutes and Centers, the private sector and the nonprofit community.

  • Supported Strategic Goal:  Advance scientific knowledge and innovation
  • Supported Strategic Objective:  Accelerate the process of scientific discovery to improve patient care

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