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CBRN Acquisition Activities

Project BioShield institutes a secure funding source for the purchase of critical medical countermeasures, such as vaccines, therapeutics, and diagnostics. Project BioShield authorizes $5.6 billion in funding over 10 years for the advanced development and purchase of priority medical countermeasures. The table below represents the Project BioShield procurement activities for medical countermeasures against chemical, biological, radiological and nuclear threats that BARDA is pursuing.

 

Anthrax

Vaccines:  recombinant Protective Antigen (rPA) Anthrax Vaccine

Notice Title

Notice Type

Date/Open

Date/Close

RFP-BARDA-08-15:  recombinant Protective Antigen (rPA) anthrax vaccine for the strategic national stockpile

Request for Proposal

12 Feb 2008

29 May 2008

HHS-BARDA-08-01-SB:  recombinant protective antigen (rPA) anthrax vaccine for the Strategic National Stockpile

Sources Sought

8 Feb 2008

21 Feb 2008

SS-DHHS-BARDA-07-01:  Anthrax recombinant Protective Antigen (rPA) vaccine for the Strategic National Stockpile (SNS)

Sources Sought

14 May 07

11 June 07

Acquisition of rPA Anthrax Vaccine for the Strategic National Stockpile

Contract with VaxGen, Inc. Terminated

19 Sept 2006

 

Award for $877,500,000  to VaxGen, Inc. (Press Release)

15 Nov 2004

 

RFP-DHHS-ORDC-04-01:  Acquisition of Licensed Anthrax Recombinant Protective Antigen (rPA) Vaccine for the Strategic National Stockpile (SNS)

Request for Proposal

9 Feb 2004

16 April 2004

RFI-ORDC-03-01:  Large-Scale Manufacturing Capabilities for Next Generation Anthrax Vaccines (e.g., Anthrax Recombinant Protective Antigen) and Safer Attenuated Vaccinia Vaccines

Request for Information

12 Aug 2003

10 Sept 2003

Vaccines:  Anthrax Vaccine Adsorbed (AVA)

Notice Title

Notice Type

Date/Open

Date/Close

RFP-DHHS-BARDA-08-26:  Anthrax Vaccine Adsorbed for the Strategic National Stockpile (SNS)

Award for $404,685,512 to Emergent Biodefense Operations

30 Sept 2008

 

Presolicitation:  Notice of Intent for Sole Source Negotiation

21 Aug 2008

5 Sept 2008

AVA for the SNS

Award for $447,650,001  to Emergent BioDefense Operations (Press Release)

25 Sept 2007

 

RFP-DHHS-OPHEMC-VB-07-02:  Anthrax Vaccine Adsorbed for the Strategic National Stockpile (SNS)

Sources Sought

18 April 2007

5 June 2007

200-2005-11811-01:  Purchase of Additional Anthrax Vaccine Adsorbed (AVA)

Contract Modification for $120 million awarded to BioPort Corporation (Press Release)

5 May 2006

 

Presolicitation:  Notice of Intent for Sole Source Negotiation

(Press Release)

3 Nov 2005

18 Nov 2005

2005-B-01696:  Purchase of BioThrax(TM)

Award for $122,737,000  to BioPort Corporation (Press Release)

5 May 2005

 

Presolicitation:  Notice of Intent for Sole Source Negotiation

4 Nov 2004

20 Nov 2004

Therapeutic Products for Inhalational Anthrax

Notice Title

Notice Type

Date/Open

Date/Close

Acquisition of Therapeutic Products for the Strategic National Stockpile

Option Exercised:  Cangene Corporation (Press Release)

28 July 2006,

 

Option Exercised: Human Genome Sciences

(Press Release)

19 June 2006

 

2004-N-01385:  Acquisition of Therapeutic Products for Treatment of Inhalational Anthrax Disease for the Strategic National Stockpile

Award for $1,797,372  to Human Genome Sciences

12 Oct 2005

 

Award for $422,880  to Cangene Corporation

12 Oct 2005

 

Request for Proposal

18 Aug 2004

 

RFI-ORDC-05-04:  Anthrax Therapeutics

Request for Information

22 Feb 2005

15 April 2005

 

 Botulism

Botulinum Heptavalent Antitoxin

Notice Title

Notice Type

Date/Open

Date/Close

2004-N-01183:  DHHS and CDC has a requirement for 200,000 Doses of Heptavalent Botulinum Immune Globulin

Award for $362,641,105 to Cangene Corporation (Press Release)

2 June 2006

 

Presolicitation:  Notice of Intent for Sole Source Negotiation

14 Sept 2004

3 Oct 2004

 

Smallpox

Modified Vaccinia Ankara (MVA)

Notice Title

Notice Type

Date/Open

Date/Close

RFP-DHHS-ORDC-VB-05-06: Draft RFP for Acquisition of Modified Vaccinia Ankara (MVA) Vaccine for the Strategic National Stockpile

Award for $500,000,000 to Bavarian Nordic

(Press Release)

4 June 2007

 

Request for Proposal

13 May 2005

3 Oct 2005

RFP-DHHS-ORDC-V and B-05-06:  Acquisition of MVA Vaccine for the Strategic National Stockpile (SNS)

Request for Proposal

28 June 2005

19 Aug 2005

 

Medical Countermeasures for Radiological/Nuclear Threats

Biodosimetry

Notice Title

Notice Type

Date/Open

Date/Close

RFI-BARDA-08-21A:  Physical and Biological Dosimetry Techniques and Devices Useful in Initial Triage After Radiologic and Nuclear Events

Request for Information

20 May 08

7 Jul 08

Therapeutics for Treating Neutropenia Resulting from Acute Exposure to Ionizing Radiation

Notice Title

Notice Type

Date/Open

Date/Close

HHS-BARDA-08-10:  Advanced Therapeutics for Treating Neutropenia Resulting from Acute Exposure to Ionizing Radiation

Request for Proposal

29 Feb 2008

23 May 08

DHHS-SOURCES-SOUGHT-ARS-MAY-2007:  Therapeutics Applicable for the Treatment of Neutropenia Resulting from Exposure to Ionizing Radiation

Sources Sought

30 May 2007

29 June 2007

DHHS-ORDC-DDA-05-12:  Medical Countermeasures to Mitigate and/or  Treat Neutropenia Alone or in combination with Co-Morbidities Associated with Acute Radiation Syndrome (ARS)

Cancelled:  Request for Proposal

7 March 2007

 

Request for Proposal

18 Nov 2005

23 Feb2006

RFI-ORDC-05-01A:  Therapeutics to Treat Neutropenia and Thrombocytopenia Associated with the Acute Radiation Syndrome (ARS)

Request for Information

20 May 2005

1 Nov 2005

RFI-ORDC-05-01:  Request for Information (RFI) ORDC-05-01 for Therapeutics to Treat Neutropenia and Thrombocytopenia Associated with the Acute Radiation Syndrome (ARS)

Request for Information

19 Oct 2004

20 Dec 2004

Acquisition of Ca DTPA and Zn DTPA to Support a Public Health Emergency Response to a Radiological or Nuclear Event

Type

Number/Link

Date/Open

Date/Close

RFP-DHHS-ORDC-DDA-05-10:  Acquisition of Ca DTPA and Zn DTPA (Calcium and Zinc Diethylenetriaminepentaacetate) to support a public health emergency response to a radiological or nuclear event

Award for $21,930,000 to Akorn, Inc

(Press Release)

30 Dec 2005

 

Presolicitation:  Notice of Intent for Sole Source Negotiation

14 Sept 2005

29 Sept 2005

Pediatric Formulation (Liquid) Potassium Iodide (KI)

Type

Number/Link

Date/Open

Date/Close

Pediatric Formulation of KI

Award for $10.2 million to Flemming & Co.

8 Feb 2006

 

Pediatric Formulation Potassium Iodide (KI) for the Strategic National Stockpile

Award for $5,700,207 to Flemming & Co.

21 March 2005

 

DHHS-ORDC-05-01:  Pediatric Formulation (Liquid) Potassium Iodide (KI)

Presolicitation:  Notice of Intent for Sole Source Negotiation

17 Dec 2004

3 Jan 2005

 

Medkits

Anthrax Antimicrobial Kits

Type

Number/Link

Date/Open

Date/Close

SS-HHS-BARDA-08-99:   Emergency Responder Anthrax Antimicrobial Kits

Sources Sought

7 March 08

21 Mar 08

Medkits

Title

Type

Date/Open

Date/Close

RFP-BARDA-08-12: Medkits

Request for Proposal

25 Jan 2008

8 Feb 08

 

Other CBRN-Related FBO Announcements:

Medical Countermeasures to Address Chemical, biological, Radiological, and Nuclear threats

Type

Number/Link

Date/Open

Date/Close

RFI-OPHEMC-06-03:  Medical Countermeasures to Address Chemical, biological, Radiological, and Nuclear threats

Request for Information

14 Sept 2006

31 Oct 2006

RFI-ORDC-05-02:  Solicitation of Comments on Implementation of the Project BioShield Act of 2004 (P.L. 108-276)

Request for Information

8 Nov 2004

24 Nov 2004